This course will emphasize the facts behind the hype in this important area. Are there synergistic interactions between drugs and botanicals (not just bad interactions)? What are the actual data for interactions (and what presumed interactions are actually anecdotal)? What theoretical interactions can occur between drugs and Botanical products? Does the dose matter in interactions? What if a Botanical can alter the AUC of a drug can they still be used together? What are the effects of a botanical that can alter the metabolism of a drug? These and other questions important to the everyday practitioner will be dealt with. Also, the mechanism of action and the clinical efficacy of some select Botanicals will be discussed.