This lecture will examine metabolic changes that occur in the cell that influence the transition from normal to cancerous. By measuring the metabolic activity of the cell, we can increase awareness of risk factors that encourage cancerous change. Many clinically researched tools exist to influence these changes, such as fermented wheat germ, resveratrol, alpha-lipoic acid, and sulforaphanes found in broccoli. However, knowing which to choose for each patient can be difficult to navigate. We will examine the research using these compounds for cancer care and prevention, and review functional medicine markers that help us decide which interventions are most important for our patients.