In this presentation, Dr. Alschuler will review the physiology of anxiety and its counterpart, resilience. Discussion will include the influence of circadian health, HPA axis dysfunction, genetic polymorphisms, hormonal influences, glucocorticoid receptor complex, organic pollutants and childhood trauma. Also included will be the important role of the amygdala resilience vs maladaptation and the role of oxytocin. Dr. Alschuler will share some of the best studied and clinically useful evidence based nutraceutical and botanical therapies, biological therapies, strategies to transition patients to natural therapies, methods to optimize circadian health and strategies to address the physiological sequelae.