There is adequate demonstration in the research literature for supplementation with chromium benefiting both hypo-and hyperglycemia. Re-examination of the literature demonstrated that the toxic dose of chromium was many times that formerly believed. The question arose as to whether we have under-dosed chromium for those with blood sugar control problems. The presentation will cover issues of safety, absorption and effectiveness of high-dose chromium supplementation (e.g. 8,000 mcg/day). Reports will be given on trials by the authors of high-dose chromium for diabetes 2.